Missouri e-Prescribing

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Missouri Electronic Prescribing

As of January 1, 2021, the State of Missouri mandated that all controlled substance prescriptions be sent electronically. To combat prescription drug abuse, MDToolbox recommends that all prescriptions be sent electronically.


MDToolbox is an approved vendor in Missouri and our e-Prescribing software, MDToolbox-Rx, meets all of the requirements for e-Prescribing and EPCS.


With MDToolbox you get:

  • Standard e-Prescribing to 99% of pharmacies nationwide
  • Controlled Substance e-Prescribing (EPCS)
  • Free Mobile e-Prescribing with every license
  • Fast Setup - most prescribers can get setup in less than 1 day
  • No Advertisements/Banners or annoying pop-ups
  • Friendly, U.S. Based Support Team
  • Secure data - we never sell your data to third party companies
  • Great tools such as: Electronic Prior Authorizations, Real-Time Price Benefits, Prescription Drug Monitoring Program (PMP) Integrations, and much more!
  • 30 day no obligation trial


Use the form to sign up today and get your first 30 days of e-Prescribing free!


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Free Trial Request

Enter your Company/Practice name and info below and we will email you both a Pricing/Info Sheet and a link to get your account started!

Please Note: Trials will only be granted to Licensed Medical Providers/Practices/Facilities-We will validate your company and identity prior to granting trial.

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e-Prescribing and EPCS in Missouri

Missouri Senate Bill 275 mandated that all controlled-substance prescriptions be prescribed electronically by January 1, 2021. The bill was signed into law by Governor Mike Parson on June 24, 2019.

See our blog post covering the mandate.


Missouri Prescription Monitoring Program

Missouri is the only state without a Prescription Monitoring Program in place.

National PMP Participation

Certain counties in Missouri participate in NABP PMP InterConnect, allowing them to share PMP data across many other states.

For More Information

Missouri Senate Bill 275 Summary

Missouri Senate Bill 275 Text


See Why Over 60,000 Medical Professionals Chose MDToolbox

Capterra Best Value for e-Prescribing Mar-20 Capterra Ease of Use for e-Prescribing Mar-20 GetApp Functionality for e-Prescribing Mar-20 5 Time Winner of White Coat Award by Surescripts *

MDToolbox is an incredible time saver! Easy interface to access a wealth of information.

Doug Waldman, MD

MDToolbox is user friendly, has made scripting a breeze. I have used a couple of other products but I have no plans to try any more! I'm staying with MDToolbox.

Moriah Moffit, MD

Very easy to use, very intuitive to use, great price. The customer service is also exceptional!

Chris Ungaro

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